This section contains information intended for health care professionals in the United States only and is not intended for the general public.
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What is IDVYNSO?
What is IDVYNSO?
What is IDVYNSO?
Important Safety Information
Important Safety Information
IDVYNSO is a complete, 1-pill, once-a-day prescription medicine used to treat Human Immunodeficiency Virus-1 (HIV-1) infection in adults. It is used to replace a person’s current HIV-1 medicines for people whose healthcare provider determines that they meet certain requirements.
HIV-1 is the virus that causes Acquired Immune Deficiency Syndrome (AIDS).
IDVYNSO contains the prescription medicines doravirine and islatravir.
IDVYNSO is a prescription medicine that is used without other Human Immunodeficiency Virus-1 (HIV-1) medicines to treat HIV-1 infection in adults to replace their current HIV-1 medicines for people whose healthcare provider determines that they meet certain requirements. HIV-1 is the virus that causes Acquired Immune Deficiency Syndrome (AIDS). IDVYNSO contains the prescription medicines doravirine and islatravir. It is not known if IDVYNSO is safe and effective in children under 18 years of age.
IDVYNSO is a prescription medicine that is used without other Human Immunodeficiency Virus-1 (HIV-1) medicines to treat HIV-1 infection in adults to replace their current HIV-1 medicines for people whose healthcare provider determines that they meet certain requirements. HIV-1 is the virus that causes Acquired Immune Deficiency Syndrome (AIDS). IDVYNSO contains the prescription medicines doravirine and islatravir. It is not known if IDVYNSO is safe and effective in children under 18 years of age.
Important Safety Information
Important Safety Information
Do not take IDVYNSO if you take certain medicines that are strong CYP3A inducers, lamivudine, or emtricitabine as they can make IDVYNSO less effective.
Talk to your healthcare provider or pharmacist if you are not sure if any of your medicines are CYP3A inducers. If you have taken any of these medicines in the past 4 weeks, talk to them before starting IDVYNSO.
Before taking IDVYNSO, tell your healthcare provider about all of your medical conditions, including if you:
- Have liver or kidney problems, or ever had hepatitis B virus infection.
- Are pregnant or plan to become pregnant. It is not known if IDVYNSO can harm your unborn baby. Tell them if you become pregnant while taking IDVYNSO.
- Are breastfeeding (nursing) or plan to breastfeed. It is not known if IDVYNSO passes into your breast milk. Talk with your healthcare provider about the following risks to your baby from breastfeeding during treatment with IDVYNSO: The HIV-1 virus may pass to your baby if your baby does not have HIV-1 infection, the HIV-1 virus may become harder to treat if your baby has HIV-1 infection, and your baby may get side effects from IDVYNSO.
- Take medicines in addition to your HIV medicine. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
- Some medicines interact with IDVYNSO. Keep a list of your medicines to show your healthcare provider and pharmacist. You can also ask your healthcare provider for a list of medicines that interact with IDVYNSO.
- Tell your healthcare provider if you have taken rifabutin in the past 4 weeks.
- Do not start taking a new medicine without telling your healthcare provider. Your healthcare provider can tell you if it is safe to take IDVYNSO with other medicines.
What are the possible side effects of IDVYNSO?
IDVYNSO may cause serious side effects, including:
Severe skin reactions. Call your healthcare provider right away if you develop a rash during treatment with IDVYNSO. Stop taking IDVYNSO and get medical help right away if you develop a painful rash with any of the following symptoms: fever, blisters or sores in the mouth, blisters or peeling of the skin, swelling of the face or lymph nodes, feeling tired or generally ill, or redness or swelling of the eyes (conjunctivitis).
The most common side effects of IDVYNSO include: diarrhea, dizziness, tiredness, stomach (abdominal) bloating, headache and weight gain.
These are not all of the possible side effects of IDVYNSO. Call your doctor for medical advice about side effects.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
Please read the accompanying Patient Information for IDVYNSO and discuss it with your healthcare provider. The physician Prescribing Information also is available.
Do not take IDVYNSO if you take certain medicines that are strong CYP3A inducers, lamivudine, or emtricitabine as they can make IDVYNSO less effective.
Talk to your healthcare provider or pharmacist if you are not sure if any of your medicines are CYP3A inducers. If you have taken any of these medicines in the past 4 weeks, talk to them before starting IDVYNSO.
Before taking IDVYNSO, tell your healthcare provider about all of your medical conditions, including if you:
- Have liver or kidney problems, or ever had hepatitis B virus infection.
- Are pregnant or plan to become pregnant. It is not known if IDVYNSO can harm your unborn baby. Tell them if you become pregnant while taking IDVYNSO.
- Are breastfeeding (nursing) or plan to breastfeed. It is not known if IDVYNSO passes into your breast milk. Talk with your healthcare provider about the following risks to your baby from breastfeeding during treatment with IDVYNSO: The HIV-1 virus may pass to your baby if your baby does not have HIV-1 infection, the HIV-1 virus may become harder to treat if your baby has HIV-1 infection, and your baby may get side effects from IDVYNSO.
- Take medicines in addition to your HIV medicine. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
- Some medicines interact with IDVYNSO. Keep a list of your medicines to show your healthcare provider and pharmacist. You can also ask your healthcare provider for a list of medicines that interact with IDVYNSO.
- Tell your healthcare provider if you have taken rifabutin in the past 4 weeks.
- Do not start taking a new medicine without telling your healthcare provider. Your healthcare provider can tell you if it is safe to take IDVYNSO with other medicines.
What are the possible side effects of IDVYNSO?
IDVYNSO may cause serious side effects, including:
Severe skin reactions. Call your healthcare provider right away if you develop a rash during treatment with IDVYNSO. Stop taking IDVYNSO and get medical help right away if you develop a painful rash with any of the following symptoms: fever, blisters or sores in the mouth, blisters or peeling of the skin, swelling of the face or lymph nodes, feeling tired or generally ill, or redness or swelling of the eyes (conjunctivitis).
The most common side effects of IDVYNSO include: diarrhea, dizziness, tiredness, stomach (abdominal) bloating, headache and weight gain.
These are not all of the possible side effects of IDVYNSO. Call your doctor for medical advice about side effects.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
Please read the accompanying Patient Information for IDVYNSO and discuss it with your healthcare provider. The physician Prescribing Information also is available.
Do not take IDVYNSO if you take certain medicines that are strong CYP3A inducers, lamivudine, or emtricitabine as they can make IDVYNSO less effective.
Talk to your healthcare provider or pharmacist if you are not sure if any of your medicines are CYP3A inducers. If you have taken any of these medicines in the past 4 weeks, talk to them before starting IDVYNSO.
Before taking IDVYNSO, tell your healthcare provider about all of your medical conditions, including if you:
- Have liver or kidney problems, or ever had hepatitis B virus infection.
- Are pregnant or plan to become pregnant. It is not known if IDVYNSO can harm your unborn baby. Tell them if you become pregnant while taking IDVYNSO.
- Are breastfeeding (nursing) or plan to breastfeed. It is not known if IDVYNSO passes into your breast milk. Talk with your healthcare provider about the following risks to your baby from breastfeeding during treatment with IDVYNSO: The HIV-1 virus may pass to your baby if your baby does not have HIV-1 infection, the HIV-1 virus may become harder to treat if your baby has HIV-1 infection, and your baby may get side effects from IDVYNSO.
- Take medicines in addition to your HIV medicine. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
- Some medicines interact with IDVYNSO. Keep a list of your medicines to show your healthcare provider and pharmacist. You can also ask your healthcare provider for a list of medicines that interact with IDVYNSO.
- Tell your healthcare provider if you have taken rifabutin in the past 4 weeks.
- Do not start taking a new medicine without telling your healthcare provider. Your healthcare provider can tell you if it is safe to take IDVYNSO with other medicines.
What are the possible side effects of IDVYNSO?
IDVYNSO may cause serious side effects, including:
Severe skin reactions. Call your healthcare provider right away if you develop a rash during treatment with IDVYNSO. Stop taking IDVYNSO and get medical help right away if you develop a painful rash with any of the following symptoms: fever, blisters or sores in the mouth, blisters or peeling of the skin, swelling of the face or lymph nodes, feeling tired or generally ill, or redness or swelling of the eyes (conjunctivitis).
The most common side effects of IDVYNSO include: diarrhea, dizziness, tiredness, stomach (abdominal) bloating, headache and weight gain.
These are not all of the possible side effects of IDVYNSO. Call your doctor for medical advice about side effects.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
Please read the accompanying Patient Information for IDVYNSO and discuss it with your healthcare provider. The physician Prescribing Information also is available.
IDVYNSO is a complete, 1-pill, once-a-day prescription medicine used to treat Human Immunodeficiency Virus-1 (HIV-1) infection in adults. It is used to replace a person’s current HIV-1 medicines for people whose healthcare provider determines that they meet certain requirements.
HIV-1 is the virus that causes Acquired Immune Deficiency Syndrome (AIDS).
IDVYNSO contains the prescription medicines doravirine and islatravir.
IDVYNSO is a prescription medicine that is used without other Human Immunodeficiency Virus-1 (HIV-1) medicines to treat HIV-1 infection in adults to replace their current HIV-1 medicines for people whose healthcare provider determines that they meet certain requirements. HIV-1 is the virus that causes Acquired Immune Deficiency Syndrome (AIDS). IDVYNSO contains the prescription medicines doravirine and islatravir. It is not known if IDVYNSO is safe and effective in children under 18 years of age.
IDVYNSO is a prescription medicine that is used without other Human Immunodeficiency Virus-1 (HIV-1) medicines to treat HIV-1 infection in adults to replace their current HIV-1 medicines for people whose healthcare provider determines that they meet certain requirements. HIV-1 is the virus that causes Acquired Immune Deficiency Syndrome (AIDS). IDVYNSO contains the prescription medicines doravirine and islatravir. It is not known if IDVYNSO is safe and effective in children under 18 years of age.
Important Safety Information Important Safety Information
Do not take IDVYNSO if you take certain medicines that are strong CYP3A inducers, lamivudine, or emtricitabine as they can make IDVYNSO less effective.
Talk to your healthcare provider or pharmacist if you are not sure if any of your medicines are CYP3A inducers. If you have taken any of these medicines in the past 4 weeks, talk to them before starting IDVYNSO.
Before taking IDVYNSO, tell your healthcare provider about all of your medical conditions, including if you:
- Have liver or kidney problems, or ever had hepatitis B virus infection.
- Are pregnant or plan to become pregnant. It is not known if IDVYNSO can harm your unborn baby. Tell them if you become pregnant while taking IDVYNSO.
- Are breastfeeding (nursing) or plan to breastfeed. It is not known if IDVYNSO passes into your breast milk. Talk with your healthcare provider about the following risks to your baby from breastfeeding during treatment with IDVYNSO: The HIV-1 virus may pass to your baby if your baby does not have HIV-1 infection, the HIV-1 virus may become harder to treat if your baby has HIV-1 infection, and your baby may get side effects from IDVYNSO.
- Take medicines in addition to your HIV medicine. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
- Some medicines interact with IDVYNSO. Keep a list of your medicines to show your healthcare provider and pharmacist. You can also ask your healthcare provider for a list of medicines that interact with IDVYNSO.
- Tell your healthcare provider if you have taken rifabutin in the past 4 weeks.
- Do not start taking a new medicine without telling your healthcare provider. Your healthcare provider can tell you if it is safe to take IDVYNSO with other medicines.
What are the possible side effects of IDVYNSO?
IDVYNSO may cause serious side effects, including:
Severe skin reactions. Call your healthcare provider right away if you develop a rash during treatment with IDVYNSO. Stop taking IDVYNSO and get medical help right away if you develop a painful rash with any of the following symptoms: fever, blisters or sores in the mouth, blisters or peeling of the skin, swelling of the face or lymph nodes, feeling tired or generally ill, or redness or swelling of the eyes (conjunctivitis).
The most common side effects of IDVYNSO include: diarrhea, dizziness, tiredness, stomach (abdominal) bloating, headache and weight gain.
These are not all of the possible side effects of IDVYNSO. Call your doctor for medical advice about side effects.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
Please read the accompanying Patient Information for IDVYNSO and discuss it with your healthcare provider. The physician Prescribing Information also is available.
Do not take IDVYNSO if you take certain medicines that are strong CYP3A inducers, lamivudine, or emtricitabine as they can make IDVYNSO less effective.
Talk to your healthcare provider or pharmacist if you are not sure if any of your medicines are CYP3A inducers. If you have taken any of these medicines in the past 4 weeks, talk to them before starting IDVYNSO.
Before taking IDVYNSO, tell your healthcare provider about all of your medical conditions, including if you:
- Have liver or kidney problems, or ever had hepatitis B virus infection.
- Are pregnant or plan to become pregnant. It is not known if IDVYNSO can harm your unborn baby. Tell them if you become pregnant while taking IDVYNSO.
- Are breastfeeding (nursing) or plan to breastfeed. It is not known if IDVYNSO passes into your breast milk. Talk with your healthcare provider about the following risks to your baby from breastfeeding during treatment with IDVYNSO: The HIV-1 virus may pass to your baby if your baby does not have HIV-1 infection, the HIV-1 virus may become harder to treat if your baby has HIV-1 infection, and your baby may get side effects from IDVYNSO.
- Take medicines in addition to your HIV medicine. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
- Some medicines interact with IDVYNSO. Keep a list of your medicines to show your healthcare provider and pharmacist. You can also ask your healthcare provider for a list of medicines that interact with IDVYNSO.
- Tell your healthcare provider if you have taken rifabutin in the past 4 weeks.
- Do not start taking a new medicine without telling your healthcare provider. Your healthcare provider can tell you if it is safe to take IDVYNSO with other medicines.
What are the possible side effects of IDVYNSO?
IDVYNSO may cause serious side effects, including:
Severe skin reactions. Call your healthcare provider right away if you develop a rash during treatment with IDVYNSO. Stop taking IDVYNSO and get medical help right away if you develop a painful rash with any of the following symptoms: fever, blisters or sores in the mouth, blisters or peeling of the skin, swelling of the face or lymph nodes, feeling tired or generally ill, or redness or swelling of the eyes (conjunctivitis).
The most common side effects of IDVYNSO include: diarrhea, dizziness, tiredness, stomach (abdominal) bloating, headache and weight gain.
These are not all of the possible side effects of IDVYNSO. Call your doctor for medical advice about side effects.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
Please read the accompanying Patient Information for IDVYNSO and discuss it with your healthcare provider. The physician Prescribing Information also is available.
Do not take IDVYNSO if you take certain medicines that are strong CYP3A inducers, lamivudine, or emtricitabine as they can make IDVYNSO less effective.
Talk to your healthcare provider or pharmacist if you are not sure if any of your medicines are CYP3A inducers. If you have taken any of these medicines in the past 4 weeks, talk to them before starting IDVYNSO.
Before taking IDVYNSO, tell your healthcare provider about all of your medical conditions, including if you:
- Have liver or kidney problems, or ever had hepatitis B virus infection.
- Are pregnant or plan to become pregnant. It is not known if IDVYNSO can harm your unborn baby. Tell them if you become pregnant while taking IDVYNSO.
- Are breastfeeding (nursing) or plan to breastfeed. It is not known if IDVYNSO passes into your breast milk. Talk with your healthcare provider about the following risks to your baby from breastfeeding during treatment with IDVYNSO: The HIV-1 virus may pass to your baby if your baby does not have HIV-1 infection, the HIV-1 virus may become harder to treat if your baby has HIV-1 infection, and your baby may get side effects from IDVYNSO.
- Take medicines in addition to your HIV medicine. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
- Some medicines interact with IDVYNSO. Keep a list of your medicines to show your healthcare provider and pharmacist. You can also ask your healthcare provider for a list of medicines that interact with IDVYNSO.
- Tell your healthcare provider if you have taken rifabutin in the past 4 weeks.
- Do not start taking a new medicine without telling your healthcare provider. Your healthcare provider can tell you if it is safe to take IDVYNSO with other medicines.
What are the possible side effects of IDVYNSO?
IDVYNSO may cause serious side effects, including:
Severe skin reactions. Call your healthcare provider right away if you develop a rash during treatment with IDVYNSO. Stop taking IDVYNSO and get medical help right away if you develop a painful rash with any of the following symptoms: fever, blisters or sores in the mouth, blisters or peeling of the skin, swelling of the face or lymph nodes, feeling tired or generally ill, or redness or swelling of the eyes (conjunctivitis).
The most common side effects of IDVYNSO include: diarrhea, dizziness, tiredness, stomach (abdominal) bloating, headache and weight gain.
These are not all of the possible side effects of IDVYNSO. Call your doctor for medical advice about side effects.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
Please read the accompanying Patient Information for IDVYNSO and discuss it with your healthcare provider. The physician Prescribing Information also is available.
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